She later regains use of her voice when the operation is completed by the Auto-Doc in Vera Keyes' hotel room. The Auto-Doc repeated the procedure for two weeks in which Christine eventually developed claustrophobia as a result. At some point, she was also locked in an Auto-Doc in the Villa's Medical District by Dean Domino, where her vocal cords were torn out. She eventually tracked him to the Sierra Madre Casino & Resort, where she was captured by his slave, Dog, and forced to work for him in breaking into the Sierra Madre while fitted with an explosive collar. Her original armor and rifle were left behind. Christine left Big Mountain with the Mark I stealth suit and resumed her quest to find Elijah.
Once Ulysses met the Think Tank and received his answers, the two separated. She recovered with him for several days in a nearby cave, where they discussed philosophy and the failure of modern civilizations like the New California Republic or Caesar's Legion to forge a new future. It was there that she was rescued by Ulysses, who blew up part of the facility just to get her out. During the course of experiments at the facility (involving jamming electrodes into the skull, and, in her own words: "Making a flashlight out of head."), her brain was damaged to the point of her losing the ability to read and write words properly (although she can still do equations and mathematical sums). The elder escaped using the ghoulified Chinese prisoners as walking bombs while Royce was wounded and taken to the Y-17 medical facility for processing. However, once she confronted her mark at Little Yangtze, they were interrupted by security robots. As word of these crimes reached the Circle, Christine was dispatched to track him down. When Elijah abandoned the Brotherhood after the defense of HELIOS One from the New California Republic Army, he left a trail of crimes across the wasteland. However, due to then- Elder Elijah's intervention, the two were separated: Santangelo stayed in the Mojave chapter, while Royce joined the Circle. During her life in California, she was in love with Veronica Santangelo.
She was a scribe in the Brotherhood of Steel before joining the Circle of Steel at the rank of knight. Royce is a member of the Circle of Steel, the internal affairs of the Brotherhood of Steel.
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